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Treatment of Parkinson’s disease tremor or rigidity, essential tremor, or dystonia using focused ultrasound

Focused ultrasound is a modern (Ernst Martin, 2009), approved (Sammy Barrit, 2025; Marjani Williams, 2025; Fusfoundation, 2025), and evidence-based (Mohit Agrawal, 2021; Alyssa Shiramba, 2025; Cesarano, S., 2024) method for the treatment of movement disorders and various other neurological diseases.

Consider Focused Ultrasound Treatment If You Have

Discuss Focused Ultrasound Treatment with Your Doctor If You Have These Symptoms:

  • Tremor (shaking hands)

  • Parkinson’s disease rigidity (stiffness)

  • Involuntary movements (cervical, myoclonic, orofacial, and other types of dystonia)

  • Neuropathic pain

  • Crying or laughter seasures (hypothalamic hamartoma)

References

  1. https://www.fusfoundation.org/posts/fda-approves-bilateral-focused-ultrasound-treatment-for-parkinsons-disease/.
  2. Barrit S, Carron R, Hariz M. Staged Bilateral MR-Guided Focused-Ultrasound Pallidothalamic Tractotomy for Parkinson’s Disease Cleared by the FDA: Caveat Emptor! Stereotact Funct Neurosurg. 2025 Nov 3:1-3 | doi: 10.1159/000548824. Epub ahead of print. PMID: 41183027.
  3. Marjani Williams Insightec Announces FDA Approval of Staged Bilateral Focused Ultrasound Treatment for Parkinson’s Disease. 2025 July 8 | https://insightec.com/news/insightec-announces-fda-approval-of-staged-bilateral-focused-ultrasound-treatment-for-parkinsons-disease/.
  4. Martin, E., Jeanmonod, D., Morel, A., Zadicario, E. and Werner, B., 2009. High‐intensity focused ultrasound for noninvasive functional neurosurgery. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society, 66(6), pp.858-861| https://doi.org/10.1002/ana.21801
  5. Agrawal, M., Garg, K., Samala, R., Rajan, R., Naik, V. and Singh, M., 2021. Outcome and complications of MR guided focused ultrasound for essential tremor: a systematic review and meta-analysis. Frontiers in neurology, 12, p.654711.| https://doi.org/10.3389/fneur.2021.654711
  6. Shiramba, A., Lane, S., Ray, N., Gilbertson, T., Srinivasaiah, R., Panicker, J., Radon, M., Osman‐Farah, J. and Macerollo, A., 2025. Efficacy and Safety of Magnetic Resonance‐Guided Focused Ultrasound Thalamotomy in Essential Tremor: A Systematic Review and Metanalysis. Movement Disorders | https://doi.org/10.1002/mds.30188
  7. Cesarano, S., Saporito, G., Sucapane, P., Bruno, F., Catalucci, A., Pistoia, M.L., Splendiani, A., Ricci, A., Di Cesare, E., Totaro, R. and Pistoia, F., 2024. Staged magnetic resonance-guided focused ultrasound thalamotomy for the treatment of bilateral essential tremor and Parkinson’s disease related tremor: a systematic review and critical appraisal of current knowledge. Frontiers in Neurology, 15, p.1409727 | https://doi.org/10.3389/fneur.2024.1409727

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